Nano Infection: Nature and NG Drugs Delivery Nature Transposon Transfection by Superparamagnetic Iron Oxide Nanoparticles (SPIONs) Vector CASE REPORT ARTICLE

The uniqueness about the case: Infection could be in the form of macro (parasite), micro (bacteria) or nano (nucleic acid) meter size. RNA virus such as SAR-Co2 in this 3 years pandemic era of COVID-19, make everybody had known the different of PCR test and antigen rapid test. This cases, reported transfection of transposons DNA, RNA which not given inflammation reaction, but genomic or epigenomic changing which driven evolution, diversity, disparity or monoculture and proteomic/metabolomic changing in other species or genus. The Natural RNAi vector transfection in tropical rainforest area is occur in daily living, especially at night when the high relative humidity near 100%. Spinel ferrite extracted from salam, kelor, papaya and many others leaves are used for a novel non-vector-mediated gene delivery into mammalian cells, but this mechanism are neglected/reckless in the discussion on blue carbon vs. blue economy G20/B20 summit in November 2022 in Bali, Indonesia. SPIONs is associated with directly healthy and environment living, indirectly help recovery or worsen of food, energy, climate, and economic crisis.

Important clinical findings: High prevalence of Down Syndrome, Parkinson Diseases, Bipolar, Autism, LGBTQAI, hypospadia and Congenital Adrenal Hyperplasia (CAH), which is due to CGG repeat, associated parallel with source of sepsis high prevalence in wet-warm climate area: SPIONs.

Primary diagnosis: Self diagnostic or in social behavior like street fashion and zebra cross fashion in rainbow flag, and primary care health center. Local leaves rich of ferromagnetic stuff act as non-vector-mediated gene or epigenetic delivery.

The lessons from the case report are breaking the taboos of Martin Bell syndrome and Escalante syndrome (CGG repeat), and known the nanomolecular cause in wet condition, which become proteomic and metabolomic neuro-enzyme blocking health laden, tropical rainforest and Nordic area.